Every cell in our body has billions of proteins which have to be shuttled across the cellular network. Therefore, cells have trafficking machineries that make sure all proteins safely arrive at their cellular destination.

 

Dysfunction of the trafficking machinery leads to cellular traffic jams, a hallmark of many devastating diseases such as Alzheimer’s disease, Parkinson and many more.

While cellular trafficking components have been investigated for decades, there are many enigmas yet to be resolved.

 

Our lab studies the cellular trafficking machineries, their regulation, their normal function, and dysfunction in human diseases.